Repetitive transcranial magnetic stimulation combined with imaginal exposure therapy for adolescents with acute stress disorder: case report

Miaomiao ZHAO; Ying LI; Haoyang ZHAO; Chaonan JIANG; Manli HUANG

doi:10.1631/jzus.B2300765

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Correspondence | Updated：2025-04-21

Repetitive transcranial magnetic stimulation combined with imaginal exposure therapy for adolescents with acute stress disorder: case report
Repetitive transcranial magnetic stimulation combined with imaginal exposure therapy for adolescents with acute stress disorder: case report
病例报告：重复经颅磁刺激联合影像暴露治疗青少年急性应激障碍
Journal of Zhejiang University-SCIENCE B (Biomedicine & Biotechnology) Vol. 26, Issue 1, Pages: 52-57(2025)
Affiliations：

1.Department of Psychiatry, the First Affiliated Hospital, Zhejiang University School of Medicine; Key Laboratory of Mental Disorder’s Management of Zhejiang Province, Hangzhou310003, China
2.Brain Research Institute of Zhejiang University, Hangzhou310003, China
3.Zhejiang Engineering Center for Mathematical Mental Health, Hangzhou310003, China
Funds：
DOI：10.1631/jzus.B2300765
CLC：
CSTR：
Received：19 October 2023，

Revised：20 February 2024，

Published Online：18 July 2024，

Published：15 January 2025
Accepted：

赵苗苗,李颖,赵昊阳等.病例报告：重复经颅磁刺激联合影像暴露治疗青少年急性应激障碍[J].浙江大学学报（英文版）（B辑：生物医学和生物技术）,2025,26(01):52-57.

Miaomiao ZHAO, Ying LI, Haoyang ZHAO, et al. Repetitive transcranial magnetic stimulation combined with imaginal exposure therapy for adolescents with acute stress disorder: case report[J]. Journal of zhejiang university-science b (biomedicine & biotechnology), 2025, 26(1): 52-57.
赵苗苗,李颖,赵昊阳等.病例报告：重复经颅磁刺激联合影像暴露治疗青少年急性应激障碍[J].浙江大学学报（英文版）（B辑：生物医学和生物技术）,2025,26(01):52-57. DOI： 10.1631/jzus.B2300765.

Miaomiao ZHAO, Ying LI, Haoyang ZHAO, et al. Repetitive transcranial magnetic stimulation combined with imaginal exposure therapy for adolescents with acute stress disorder: case report[J]. Journal of zhejiang university-science b (biomedicine & biotechnology), 2025, 26(1): 52-57. DOI： 10.1631/jzus.B2300765.

摘要

青少年急性应激障碍（ASD）的症状通常是不典型且偏离常态的，因此未能得到足够重视。及时干预有可能减轻ASD向创伤后应激障碍（PTSD）发展。但对青少年急性应激障碍的诊断和治疗，尚缺乏经验支持和令人信服的证据。本文所述案例围绕两名被诊断为ASD的青少年展开，患者分别经历了反复出现的侵入性痛苦回忆、忍受负面情绪、逃避和睡眠中断。两名青少年在接受重复经颅磁刺激（rTMS）和想象暴露的联合治疗后，精神症状显著改善。此外，在1个月的随访期间，两例患者病情均保持稳定。上述病例表明，rTMS和想象暴露的结合有望成为青少年ASD的治疗策略，值得开展进一步研究。

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